JAMA Network, May 30, 2023
This study involving 2 large, community-based, longitudinal, cohort studies whether adding 2 markers—coronary artery calcium score and polygenic risk score—to traditional risk factor–based scores improves predicting coronary heart disease among middle-aged to older adults.
JAMA. 2023; 329(20):1768-1777. doi: 10.1001/jama.2023.7575
Sadiya S. Khan, MD, MSc; Wendy S. Post, MD; Xiuqing Guo, PhD; Jingyi Tan, MA; Fang Zhu, MSc, MPH; Daniel Bos, MD, PhD; Bahar Sedaghati-Khayat, MSc; Jeroen van Rooij, PhD; Aaron Aday, MD, MS; Norrina B. Allen, PhD; Maxime M. Bos, PhD; André G. Uitterlinden, PhD; Matthew J. Budoff, MD; Donald M. Lloyd-Jones, MD, ScM; Jonathan D. Mosley, MD, PhD; Jerome I. Rotter, MD; Philip Greenland, MD; Maryam Kavousi, MD, PhD
